The city of Kulob, more often seen written Russian style as Kulyab, is located in the eastern part of Khatlon province. The city is pleasant enough, and does have enough to keep you busy for a day or so. Kulob is home to the Hamadoni mausoleum and it is close to the Hulbuk citadel and the Khoja Mumin salt mountain, and it is a good place to start a trip from if you are going to Shuroobod District or to the Childukhtaron mountains.
More information on visiting Kulob City coming by mid-2016. For a look at the city, watch these two very well produced drone videos: